• Jingwen & Luo

    Integration

    of quantitative genomics and neurobiology to understand Autism Spectrum Disorders

  • Family-Based Studies

    lead to better understanding of neurodiversity

  • Modeling Behavioral Traits

    in experimental organisms will lead to new therapies

  • Welcome to ASPE

    The Perelman School of Medicine at the University of Pennsylvania established ASPE, the Autism Spectrum Program of Excellence, in 2017 to significantly improve the understanding of the genetic causes of Autism Spectrum Disorder (ASD) in order to energize the research and clinical community across the globe. The ASPE program was made possible by a generous donation from an anonymous philanthropist.

    Genetic studies of ASD will give us greater insight into the genetic roots of the entire autism spectrum. A major focus of ASPE will be on the NRXN1 gene, which codes for the protein neurexin 1 and has been associated with autism spectrum disorder and other psychiatric and neurodevelopmental disorders.

    Latest News

    Mutations in Life’s “Essential Genes” Tied to Autism
    Mutations in Life’s “Essential Genes” Tied to Autism

    Penn Study Points to High Priority Genes as Potential Research Targets in Autistic Spectrum Disorder

    More Info
    New Mouse Model Points to Drug Target Potentially Useful for Increasing Social Interaction in Autism
    New Mouse Model Points to Drug Target Potentially Useful for Increasing Social Interaction in Autism

    A study of a new mouse model identifies a drug target that has the potential...

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    Penn Study on Fragile X Syndrome Uses Fruitfly’s Point of View to Identify New Treatment Paths
    Penn Study on Fragile X Syndrome Uses Fruitfly’s Point of View to Identify New Treatment Paths

    Fragile X syndrome (FXS) is the most common genetically inherited cause of intellectual disability in...

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    Events

    Mini-symposium on Autism Spectrum Disorders

    Penn will host a mini-symposium for ASPE on October 22, 2018 to review early findings and stimulate new research avenues.

    Title:  Exploring the phenotypic, genetic, and biologic diversity of the autism spectrum

    Time:  Monday, October 22, 2018 3:00-5:00pm

    Place:  Jordan Medical Education Center Law Auditorium

     

    Contact us for info regarding the symposium.