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Research
Integration of quantitative genomics and neurobiology to understand Autism Spectrum Disorders.
Family-Based Studies
Lead to better understanding of neurodiversity.
Welcome to ASPE
The Perelman School of Medicine at the University of Pennsylvania established ASPE, the Autism Spectrum Program of Excellence, in 2017 to improve the quality of life for autistic individuals and their families through research. Through the ASPE Study, we hope to significantly inform the understanding of the genetic causes of autism in order to energize the research and clinical community across the globe. The ASPE program was made possible by a generous donation from an anonymous philanthropist.
A major focus of ASPE is on the NRXN1 gene (2p16.3 deletion), which codes for the protein neurexin 1 and has been associated with autism and other psychiatric and neurodevelopmental disorders. ASPE is working to translate this biological research into improved treatments, services, and support programs, as well as increased acceptance and advocacy for individuals on the spectrum.
Latest News
Happy Autism Acceptance Month from the Autism Spectrum Program of Excellence (ASPE)! Autism Acceptance Month is a reminder to embrace and honor individuality every single day, not just during this special month. We hope our…
The ASPE Team is grateful to have had the opportunity to connect with families and fellow researchers at the 1st In-Person NRXN1 Research and Family Conference, held February 20–22 in Philadelphia. Nearly 40 ASPE trainees,…
Every person has a unique mix of strengths, needs, and ways of experiencing the world. The Autism Spectrum Program of Excellence (ASPE) Study explores how differences in DNA (genotype) might help explain the wide range…
