Who Can Participate

An important part of understanding the biological basis of ASD is learning about what makes individuals more vulnerable and what protects them. A family-based genetic approach, such as the one in this study, can lead to breakthroughs in elucidating these vulnerability and protective factors. A similar approach will be used to study the NRXN1 gene.

Since ASD and NRXN1 variants may run in families, we would also like to recruit any first-degree family members (parents, siblings, children) and second- and third-degree relatives (grandparents, grandchildren, aunts, uncles, nephews, nieces, half-siblings, first cousins) who are willing to participate in the study.

Extended family members may include children ages 3 years and over. Our research team is especially interested in families with multiple individuals with ASD. We welcome all inquiries regarding research eligibility.

Autism Spectrum Disorder

The ASPE Program is recruiting adults and children ages 3 years and over with a diagnosis (or suspected diagnosis) of autism spectrum disorder (ASD) without intellectual disability. This may include individuals with Asperger syndrome, pervasive developmental disorder (PDD-NOS) and social communication disorder.

NRXN1

The ASPE Program is also recruiting adults and children ages 3 years and over with a NRXN1 gene variant or a 2p16.3 copy number variant (e.g. deletion). Individuals with a NRXN1 gene variant do not need an ASD diagnosis (or suspected diagnosis) to participate. Additionally, we are recruiting individuals with a NRXN1 mutation both with and without intellectual disability.

Interested in participating? Click here.