Marc Fuccillo, M.D., Ph.D., is an Associate Professor of Neuroscience at the Perelman School of Medicine. The Fuccillo lab studies neural circuits and synaptic adhesion molecules that are relevant for brain disease using mice as a model system. Marc obtained his PhD in Gord Fishell’s lab studying developmental control of cell diversity, and completed postdoctoral studies with Rob Malenka and Tom Südhof, studying the synaptic and behavioral functions of synapse-associated molecules such as Neurexin1. The Fuccillo lab uses in vitro and in vivo cellular electrophysiology, imaging and perturbation of neural activity, and quantitative behaviors to examine how dysfunction of neural signals within specific circuits impacts motor control and reinforcement learning. For ASPE, the Fuccillo lab is particularly interested in how autism-associated genetic disruptions alter synapse function and behavior.